Bad Neighborhoods May Be Bad for Your DNA
It has long been known
that people who live in unsafe neighborhoods suffer poorer health and
increased risk for death. Now researchers have found that living in
these areas is associated with shorter telomere length, a marker of
aging cells.
Telomeres, which lie
at the ends of chromosomes, are structures involved in the replication
of DNA molecules. Each time a cell divides, telomeres becomes shorter, a
process associated with aging, illness and death.
Researchers studied
2,981 Dutch people aged 18 to 65, measuring telomere lengths in their
white blood cells. They assessed neighborhood quality by asking
residents about high noise levels,
vandalism in the neighborhood, and
feeling unsafe walking alone. The study is in PLOS One.
After controlling for a
range of socioeconomic, health and lifestyle characteristics, they
found that the greater the residents’ degree of unfavorable perceptions
about their neighborhoods, the shorter the average telomere length in
their cells.
The lead author,
Mijung Park, an assistant professor of nursing at the University of
Pittsburgh, said that the results should be interpreted cautiously — it
is an observational study, and does not prove cause and effect.
Still, she said, “When
we look at two people of the same age and gender and other
characteristics, we find that those who live in bad neighborhoods are
biologically older than those who do not by about 12 years.”
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